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Dr. Chen’s primary research interest includes the study of the molecular mechanisms that control inflammation and cell proliferation via protein ubiquitination. Specifically, over the last four years, he has successfully identified and characterized over 10 novel ubiquitin E3 ligases. Dr. Chen’s second area of research interest is in the small molecule drug design. He has successfully designed and synthesized a novel series of first-in-class small molecule FBXO3 protein inhibitors. One of his compound designs, BC-1215, is currently used as a molecular tool for investigating the ubiquitination pathway.